Renal failure or hypernatremia; in conjuction with hexamine mandelate or hexamine hippurate therapy because an acidic urine is needed. Caution is advised in overt and occult cardiac failure. Concomitant use of urinary alkalinisers and quinolone antibiotic should be avoided; crystalluria may be more likely to occur in alkaline urine. Not responsible with your country’s customs, please check with your country’s customs before you buy. Also allow some time for your country's customs clearance time, because the delays usually come from Customs Our customer service representative works on 24/7 basis. Your satisfaction is of utmost importance to us. Always feel free to email us with any questions or concerns and we would personally get back to you. Please email us through eBay by clicking the ".